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Chaple, D. R.
- Development of UV Spectrophotometric Methods for Simultaneous Estimation of Atorvastatin and Telmisartan in Combined Dosage Form Using Simultaneous Equation Method
Authors
1 J. L. Chaturvedi College of Pharmacy, Electronic Zone Building MIDC, Hingna Road, Nagpur, Maharashtra, Pin 400016, IN
Source
Asian Journal of Research in Chemistry, Vol 4, No 11 (2011), Pagination: 1777-1779Abstract
A new, simple, rapid and novel spectrophotometric method has been developed for simultaneous estimation of Atorvastatin and Telmisartan For this, simultaneous equation method is used. The method involved measurement of absorbance at two wavelengths, 246.20 nm and 290 nm, _ max of Atorvastatin and Telmisartan respectively. Beer's law obeyed in concentration range of 5-30 μg/ mL and 5-30 μg/ mL for Atorvastatin and Telmisartan respectively. The proposed method is recommended for routine analysis since it is rapid, simple, accurate and also sensitive and specific by no heating and no
organic solvent extraction. This paper describes the development and validation of UV spectroscopic method for Simultaneous estimation of Atorvastatin and Telmisartan in combined solid dosage form.
Keywords
Atorvastatin, Telmisartan, Simultaneous Equation Method.- Simultaneous Estimation of Azithromycin and Ambroxol Hydrochloride in Combined Tablet Dosage Form by Multicomponent Mode of Analysis
Authors
1 J. L. Chaturvedi College of Pharmacy, MIDC, Hingna Road, Electronic Zone Building, Nagpur-440016, IN
Source
Asian Journal of Research in Chemistry, Vol 3, No 2 (2010), Pagination: 296-298Abstract
A simple, precise and accurate spectrophotometric method has been developed for simultaneous estimation of ambroxol hydrochloride and azithromycin in combined dosage form using multicomponrent mode of analysis. It involves the measurements of absorbance at five selected wavelengths 215 nm, 258 nm, 260 nm, 300 nm and 307 nm using methanol and sodium hydroxide (0.2 N) as a solvent. Linearity was observed in the range of 10-80 μg/mL for mixture. The recovery studies confirmed the accuracy of the proposed method. The results were validated as per ICH guidelines.Keywords
Azithromycin, Ambroxol Hydrochloride, Multicomponent Mode.- Simultaneous Spectrophotometric Estimation of Ofloxacin and Ornidazole in Tablet Dosage Form
Authors
1 Sharad Pawar College of Pharmacy, Wanadongri, Higana Road, Nagpur-441110, Maharashtra, IN